Liposomes belong to the colloidal delivery systems of bioactive substances which possess the ability to transfer them and hence improve their effectiveness. Depending on the preparation method, in combination with the physicochemical characteristics of their structural units, the dimensions of the liposomes range from nanometers to a few micrometers.
In the early 1960s, there existed a trend for the study of the biophysical properties of colloidal systems that were composed of lipids and phospholipids with the goal of understanding the biophysical functions of cells. A.D. Bangham, a biophysicist,studied colloidal lipid dispersions in order to mimic the structure and functionality cell membranes and study their functionality.
As long as the liposomes are constructed from similar materials to human cells they benefit over other delivery carriers due to their structural similarity to human membranes. They have the ability not only to deliver lipophilic bioactive substances that do not dissolve easily in an aqueous media and exhibit problems with their absorption and bioavailability e.g., vitamins, curcumin, etc. but also ameliorate the rate of the dialysis and absorption via the gastrointestinal lumen of other water-insoluble amphiphilic substances.
Liposomes possess the ability to deliver bioactive substances and improve their transit across the barriers of the gastrointestinal tract. They are hence deliver vehicles of bioactive substances.
Liposomal technology, especially the innovative technology of supramolecular phospholipids complexes possessing a double layerlipid structure, can improve the therapeutic efficacy of dietary supplements – a ground-breaking discovery in this field. This pioneering technology increases the effects of the final dosage form of dietary supplements.
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